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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3A All Species: 32.73
Human Site: T1247 Identified Species: 72
UniProt: O14802 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14802 NP_008986.2 1390 155641 T1247 G V K G T R T T S N N T Y E V
Chimpanzee Pan troglodytes XP_507865 1349 150791 T1206 G V K G T R T T S N N T Y E V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536399 1390 155706 T1247 G V K G T R T T S N N T Y E V
Cat Felis silvestris
Mouse Mus musculus P08775 1970 217158 T1358 D V D P V R T T S N D I V E I
Rat Rattus norvegicus O54889 1716 194174 W1520 Y D T E E S L W C Q V T V K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514706 1382 154562 T1239 G V K G T K T T S N N T Y E V
Chicken Gallus gallus Q5ZL98 1390 155685 S1247 G V K G T K T S S N N T Y E V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P04052 1887 209150 S1350 D V D P I R T S S N D I C E I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P16356 1852 203961 T1346 Q I D P V R T T S N D I C E I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P18616 1840 204671 T1350 D V D P K R T T S N H L I E I
Baker's Yeast Sacchar. cerevisiae P04051 1460 162283 T1315 G V I G S R T T T N H V L E V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 N.A. 98.8 N.A. 26 26.8 N.A. 95.9 96.2 N.A. N.A. N.A. 27.4 N.A. 27.8 N.A.
Protein Similarity: 100 96.6 N.A. 99.5 N.A. 40.8 43.9 N.A. 98.1 98.5 N.A. N.A. N.A. 43.1 N.A. 43.9 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 46.6 6.6 N.A. 93.3 86.6 N.A. N.A. N.A. 40 N.A. 40 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 60 20 N.A. 100 100 N.A. N.A. N.A. 60 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.7 51.1 N.A.
Protein Similarity: N.A. N.A. N.A. 43.9 68.2 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 19 0 0 % C
% Asp: 28 10 37 0 0 0 0 0 0 0 28 0 0 0 0 % D
% Glu: 0 0 0 10 10 0 0 0 0 0 0 0 0 91 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 55 0 0 55 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % H
% Ile: 0 10 10 0 10 0 0 0 0 0 0 28 10 0 37 % I
% Lys: 0 0 46 0 10 19 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 0 10 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 91 46 0 0 0 0 % N
% Pro: 0 0 0 37 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 73 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 10 10 0 19 82 0 0 0 0 0 0 % S
% Thr: 0 0 10 0 46 0 91 73 10 0 0 55 0 0 0 % T
% Val: 0 82 0 0 19 0 0 0 0 0 10 10 19 0 55 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 46 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _